MPN

Introduction

Myeloproliferative neoplasms (MPN) refers to a group of diseases in which the bone marrow makes too many of one or more types of blood cells—these include WBCs, RBCs, or platelets.

Causes

MPN has no clear causes. But certain factors increase your risk of getting the condition.

Old age: Individuals over 60 have a higher chance of developing myelofibrosis, polycythemia vera and primary myelofibrosis
Gender: Polycythemia vera, primary myelofibrosis and chronic myelogenous leukemia are more common in men
Women have a higher chance of getting essential thrombocytosis

Symptoms

Individuals with MPN usually experience

Fatigue and tiredness
Shortness of breath during exertion
Pale skin
Loss of appetite
Weight loss
Bone pain
Night sweats
Itching
Infections and fever
A painful enlarged liver or spleen
Weight loss without trying
Blood clots

Diagnosis

MPNs are usually detected during blood tests. There are a number of tests and tools doctors use to confirm a diagnosis:

Physical exam and history
Blood tests:
- A blood smear
- A complete blood count
Bone marrow tests like aspiration and biopsy to see how your bone marrow looks.
Cytogenetic testing, which tries to find abnormalities in your cell’s DNA.

Treatment

Treating MPN will largely depend on the type and severity of the condition. Common treatment methods are:

Chemotherapy
Gene therapy
Stem cell transplant

Patients are our number one priority. We are committed to their health and wellbeing. It is this dedication that guides us to give our very best, and our multidisciplinary team of trained professionals work together to ensure quality care. If you’re showing any symptoms of MPN listed above, consult the team of experts at Haemato Oncology Care Centre (HOCC) without any delay.

Because Blood Count Matters, Count On Us.

Book an Appointment

Designed and developed by Trizone Healthcare